Human ITPR1 / IP3 Receptor Type 1

Rabbit

Human, Monkey, Mouse, Rat, Bovine (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Affinity purified

Unmodified

Synthetic peptide corresponding to aa 1892-1911 (N1892KKKDDEVDRDAPSRKKAKE1911) of the cytoplasmic C-Terminus domain of human IP3R-I (inositol 1,4,5-triphosphate receptor (type-I)). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%); Hamster, Elephant, Panda, Horse (95%); Opossum (85%).

aa1892-1911

Recognizes human IP3R-I. Detects a band of ~240kD by Western Blot. Species cross-reactivity: mouse, rat and canine.

• IHC
• IHC - Paraffin (5 µg/ml)
• IHC - Frozen (1:125)
• ICC
• Western blot (1:500)
• Immunoprecipitation

Immunohistochemistry: LS-B2640 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2640 was determined to be 5 ug/ml.

PBS, 1 mg/ml BSA, 0.05% Sodium Azide

Store at 4°C or -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q14643 NCBI: NM_001099952 NP_002213.5