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ITPKA

inositol-trisphosphate 3-kinase A

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-triphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-triphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.

Gene Name: inositol-trisphosphate 3-kinase A
Family/Subfamily: Non-protein Kinase , ITPK
Synonyms: ITPKA, IP3-3KA, IP3KA, InsP 3-kinase A, IP3 3-kinase A, IP3K A
Target Sequences: NM_002220 NP_002211.1 P23677

☰ Filters
Antibodies (21)
Proteins (3)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (21)
Recombinant (1)
ITPKA (25)
Human (22)
Mouse (14)
Rat (7)
Bovine (1)
Dog (1)
Pig (1)
IHC (1)
WB (21)
ELISA (15)
ICC (1)
IF (4)
IP (1)
Peptide-ELISA (2)
rabbit (21)
IgG (17)
polyclonal pc (21)
96-Well Microplate (1)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (11)
aa1-30 (7)
aa345-375 (7)
370-450 aa, C-terminal (1)
His431 (1)
aa396-445 (1)
No (25)
Adherent Cell Cultures (1)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
Select
ITPKA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
ITPKA Antibody - Immunofluorescent analysis of ITPKA staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with Alexa Fluor 647-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Select
ITPKA Rabbit anti-Human Polyclonal Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
ITPKA Antibody - Western blot of IP3KA antibody
Select
ITPKA Rabbit anti-Human Polyclonal (370-450 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITPKA Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
ITPKA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ITPKA Antibody - Western blot analysis of extracts from HUVEC cells, using IP3KA antibody.
Select
ITPKA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ITPKA Antibody - Western blot analysis of lysates from HUVEC cells, using IP3KA Antibody. The lane on the right is blocked with the synthesized peptide.
Select
ITPKA Rabbit anti-Human Polyclonal (aa396-445) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ITPKA Antibody - Western blot of anti-ITPKA Antibody in mouse cerebellum tissue lysates (35 ug/lane). ITPKA(arrow) was detected using the purified antibody.
Select
ITPKA Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
WB
Unconjugated
400 µl/$393
ITPKA Antibody - Western blot of hITPKA-E360 in K562 cell line and mouse lung tissue lysates (35 ug/lane). ITPKA (arrow) was detected using the purified antibody.
Select
ITPKA Rabbit anti-Human Polyclonal (aa345-375) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
ITPKA Antibody - Western blot of IP3KA (H431) pAb in extracts from HuvEc cells.
Select
ITPKA Rabbit anti-Human Polyclonal (His431) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
ITPKA Protein - Purified recombinant protein ITPKA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
50.8 kDa
20 µg/$1,107
ITPKA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
50.8 kDa
100 µg/$494
ITPKA ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
ITPKA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
50.8 kDa
20 µg/$150
Viewing 1-25 of 25 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).