Mouse ITGB4 / Integrin Beta 4
(tested or 100% immunogen sequence identity)
Also available Unconjugated
or conjugated with Biotin
Protein G purified
- IHC - Frozen
- Western blot
- Flow Cytometry (1:1 - 1:5)
- (applications tested for the base form of this product only)
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including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
TSP-180 purified from Balb/c murine carcinoma.
Recognizes mouse integrin beta 4 (CD104), a 200kD glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. Expression of CD104 is localized to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurons, carcinoma cell lines and a subset of endothelial cells. The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane. Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul Method sheets are available on request.
Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
For research use only.
This antibody carries the LSBio 100% Guarantee.