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Catalog Number Size Price
LS-C14097-100 100 µg $826 
Antibody

Monoclonal Mouse anti‑Human ITGB4 / Integrin Beta 4 Antibody (IHC) LS‑C14097

Monoclonal Mouse anti‑Human ITGB4 / Integrin Beta 4 Antibody (IHC) LS‑C14097

Antibody:
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-Fr, IP, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$826
LS-C14097-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-Fr, IP, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Integrin Beta 4 antibody LS-C14097 is an unconjugated mouse monoclonal antibody to human Integrin Beta 4 (ITGB4). Validated for Flow, Func, IHC and IP.
Target
Human ITGB4 / Integrin Beta 4
Synonyms
ITGB4 | CD104 | Integrin beta-4 | Integrin Beta 4 | gp150 | CD104 antigen | Integrin beta-4 subunit | Integrin, beta 4
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Human squamous cell carcinoma cells (SCC9).
Specificity
Human b4 integrin (CD104).
Applications
  • IHC
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry
  • Functional Assay
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Inhibition of cell attachment: inhibits SCC9 cell adhesion to human laminin and laminin GD-2 peptide, but not to EHS laminin, type IV collagen or fibronectin. Does not inhibit SKOV-3 cell adhesion to laminin, fibronectin or type IV collagen. Immunohistochemistry: on acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue. Flow cytometry: stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelium (HUVEC). Stains RKO or K562 cells transfected for CD104 expression. Does not stain monocytes, neutrophils, lymphocytes, T cells, B cells or platelets. Immunoprecipitation: precipitates PAGE bands of 66, 76, 120, 135 and 200kD (reduced) or 66, 110, 125, 130 and 190kD (non-reduced) from surface-biotinylated SCC9 cells.
Presentation
0.02 M PB, pH 7.6, 0.25 M NaCl, 0.1% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGB4 / Integrin Beta 4
P16144 NM_000213 NP_000204.3

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/19/2024