LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-ITGB4 / Integrin Beta 4 Antibody (FITC) LS-C44754

Note: This antibody replaces LS-C57923

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $235
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ITGB4 / Integrin Beta 4 Antibodies

Anti-ITGB4 / Integrin Beta 4 Antibody (clone 450-9D, Azide-free) LS-C14106
Mouse Monoclonal [clone 450-9D] (IgG1) to Human ITGB4 / Integrin Beta 4
Human
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated, Azide-free
Anti-ITGB4 / Integrin Beta 4 Antibody (clone 439-9B) IHC-plus™ LS-B3778
Rat Monoclonal [clone 439-9B] (IgG2b) to Human ITGB4 / Integrin Beta 4
Human
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-ITGB4 / Integrin Beta 4 Antibody (aa1619-1822, clone 10B10D5) IHC-plus™ LS-B9845
Mouse Monoclonal [clone 10B10D5] (IgG1) to Human ITGB4 / Integrin Beta 4
Human
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2a) to Mouse ITGB4 / Integrin Beta 4
Mouse
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Mouse ITGB4 / Integrin Beta 4
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Fluorescein. Also available Unconjugated or conjugated with Biotin, RPE.
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:5)
  • (applications tested for the base form of this product only)

Specificity and Use

ITGB4 / Integrin Beta 4 antibody was raised against tSP-180 purified from Balb/c murine carcinoma.
Recognizes mouse integrin beta 4 (CD104), a 200kD glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. Expression of CD104 is localized to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurons, carcinoma cell lines and a subset of endothelial cells. The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane. Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About ITGB4 / Integrin Beta 4

P16144 NM_000213 NP_000204.3

ITGB4 Antibody, CD104 Antibody, Integrin beta-4 Antibody, Integrin Beta 4 Antibody, gp150 Antibody, CD104 antigen Antibody, Integrin beta-4 subunit Antibody, Integrin, beta 4 Antibody

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins.

Requested From: United States
Date Requested: 12/5/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number