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Catalog Number Size Price
LS-C499168-50 50 µg $294 
LS-C499168-100 100 µg $360 
Antibody

Polyclonal Rabbit anti‑Human ITGB4 / Integrin Beta 4 Antibody (Biotin) LS‑C499168

Polyclonal Rabbit anti‑Human ITGB4 / Integrin Beta 4 Antibody (Biotin) LS‑C499168

Antibody:
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Price
Catalog Number
$294
LS-C499168-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:

Specifications

Description
Integrin Beta 4 antibody LS-C499168 is a biotin-conjugated rabbit polyclonal antibody to human Integrin Beta 4 (ITGB4). Validated for ELISA.
Target
Human ITGB4 / Integrin Beta 4
Synonyms
ITGB4 | CD104 | Integrin beta-4 | Integrin Beta 4 | gp150 | CD104 antigen | Integrin beta-4 subunit | Integrin, beta 4
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with HRP, FITC.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Integrin beta-4 protein (1401-1533AA)
Specificity
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).
Applications
  • ELISA
  • Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGB4 / Integrin Beta 4
P16144 NM_000213 NP_000204.3

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/23/2024