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Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody LS-C13866

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Mouse Monoclonal (IgG1,k) to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC, ICC, Western blot
Unconjugated

Details

Human ITGB3 / Integrin Beta 3 / CD61
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Protein G purified

Applications

IHC, ICC (5 - 20 µg/ml), Western blot

Specificity and Use

ITGB3 / Integrin Beta 3 / CD61 antibody was raised against human platelet membrane fraction.
Recognizes Integrin b3 (CD61), as determined by an independent laboratory. Mr ~115kD. Species cross-reactivity: Human.
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry. Immunocytochemistry: 5-20 ug/ml showed positive immunostaining for Integrin 3 (CD61) in HuVec cells fixed with 4% paraformaldehyde followed by permeabilization with 0.25% Triton X-100. Western Blot: Detects Integrin 3 (CD61) in WM852 and 1205Lu whole cell extracts. Immunohistochemistry: Detects Integrin 3 (CD61) in malignant melanoma sections.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ITGB3 / Integrin Beta 3 / CD61

P05106 NM_000212 NP_000203.2

ITGB3 Antibody, BDPLT2 Antibody, CD61 antigen Antibody, GT Antibody, gp3A Antibody, CD61 Antibody, GPIIIa Antibody, Integrin beta-3 Antibody

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.

Requested From: United States
Date Requested: 9/27/2016

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