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Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1) LS-C44640

Note: This antibody replaces LS-C57860, LS-C44645

Ordering

Wt. Vol. Conc. Price
250 µg - 1 mg/ml $325
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ITGB3 / Integrin Beta 3 / CD61 Antibodies

Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (N-Terminus) IHC-plus™ LS-A9416
Rabbit Polyclonal to Human ITGB3 / Integrin Beta 3 / CD61
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (FITC) LS-C130089
Mouse Monoclonal (IgG1) to Pig ITGB3 / Integrin Beta 3 / CD61
Pig, Human, Bovine, Dog, Horse
Flow Cytometry
FITC Conjugated

100% Guaranteed 100% Guaranteed
Hamster Monoclonal [clone HM beta 3.1] (IgG) to Mouse ITGB3 / Integrin Beta 3 / CD61
Mouse, Rat
Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Mouse ITGB3 / Integrin Beta 3 / CD61
Hamster
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Monoclonal [HM beta 3.1]
Unconjugated. Also available conjugated with Biotin, FITC, FITC, RPE.
Protein G purified
Unmodified. Also available Low Endotoxin.

Applications

  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:25)
  • (applications tested for the base form of this product only)

Specificity and Use

ITGB3 / Integrin Beta 3 / CD61 antibody was raised against mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About ITGB3 / Integrin Beta 3 / CD61

P05106 NM_000212 NP_000203.2

ITGB3 Antibody, BDPLT2 Antibody, CD61 antigen Antibody, GT Antibody, gp3A Antibody, CD61 Antibody, GPIIIa Antibody, Integrin beta-3 Antibody

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.

Requested From: United States
Date Requested: 12/3/2016

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