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Anti-ITGB3 / Integrin Beta 3 / CD61 Antibody (Biotin) LS-C13880

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Mouse Monoclonal (IgG1) to Human ITGB3 / Integrin Beta 3 / CD61
Human
Flow Cytometry
Biotin Conjugated

Details

Human ITGB3 / Integrin Beta 3 / CD61
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Biotin
Ion exchange chromatography

Applications

Flow Cytometry

Specificity and Use

ITGB3 / Integrin Beta 3 / CD61 antibody was raised against platelet plasma membrane.
Recognizes the integrin beta 3 chain (105kD). Inhibits platelet aggregation and activation induced by thrombin and collagen. Species cross-reactivity: Reported to cross-react with baboon.
Suitable for use in Flow Cytometry. Flow Cytometry: Neat. 10 ul of the optimal dilution to label 1E6 cells or 100 ul whole blood.

Packaging

PBS, pH 7.2, 1% BSA, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About ITGB3 / Integrin Beta 3 / CD61

P05106 NM_000212 NP_000203.2

ITGB3 Antibody, BDPLT2 Antibody, CD61 antigen Antibody, GT Antibody, gp3A Antibody, CD61 Antibody, GPIIIa Antibody, Integrin beta-3 Antibody

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.

Requested From: United States
Date Requested: 9/29/2016

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