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ITGAX / CD11c
integrin, alpha X (complement component 3 receptor 4 subunit)
ITGAX / CD11c is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | integrin, alpha X (complement component 3 receptor 4 subunit) |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGAX, CD11c antigen, Integrin alpha-X, Leu M5, alpha subunit, p150 95 integrin alpha chain, SLEB6, CD11C, Leu M5 |
| Target Sequences: | NM_000887 NP_000878.2 P20702 |
Publications (5)
1
CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. Sadhu C, Ting HJ, Lipsky B, Hensley K, Garcia-Martinez LF, Simon SI, Staunton DE. Journal of leukocyte biology. 2007 81:1395-403.
[PubMed:17389580]
Related Antibodies: LS-C40809.
2
Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, Arrey F, Park CG, Steinman RM, Mnz C. Blood. 2008 112:1231-9.
[PubMed:18519810]
[PMC:PMC2515117]
Related Antibodies: LS-C40809.
3
Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. Asai A, Okajima F, Nakagawa K, Ibusuki D, Tanimura K, Nakajima Y, Nagao M, Sudo M, Harada T, Miyazawa T, Oikawa S. Journal of lipid research. 2009 50:957-65.
[PubMed:19114730]
[PMC:PMC2666182]
Related Antibodies: LS-C40809.
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Products
Antibodies
(156)
Proteins
(6)
Type
Over-Expression Lysate
(2)
Primary
(156)
Recombinant
(4)
Target
ITGAX / CD11c
(162)
Reactivity
Human
(109)
Mouse
(51)
Rat
(5)
Bovine
(1)
Dog
(4)
Monkey
(11)
Non-Human Primate
(5)
Primate
(4)
Application
IHC
(56)
IHC-Fr
(26)
IHC-P
(13)
WB
(43)
Flo
(104)
Block
(2)
ELISA
(16)
Func
(2)
ICC
(2)
IF
(18)
IHC-Pfa
(1)
IP
(27)
Peptide-ELISA
(3)
Host
rabbit
(40)
mouse
(81)
hamster
(16)
hamster-armenian
(15)
rat
(4)
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(3)
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(49)
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(5)
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(52)
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(13)
IgG2a
(9)
IgG2b
(1)
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(3)
IgM
(1)
Clonality
monoclonal mc
(115)
polyclonal pc
(38)
recombinant monoclonal rmc
(3)
Clone
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(1)
223H7
(3)
3.9
(17)
428CT12.2.6.4
(2)
5D11
(1)
6G2D1
(1)
BAQ153A
(1)
BU15
(24)
CA11.6A1
(1)
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(1)
FK24
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HC1/1
(2)
ITGAX/1242
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ITGAX/1243
(2)
ITGAX/1284
(2)
N418
(29)
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(3)
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(10)
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(15)
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(2)
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(3)
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(5)
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(1)
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(1)
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(1)
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(19)
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(7)
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(8)
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(16)
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(1)
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(2)
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(58)
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aa143-344
(8)
aa907-1115
(8)
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(7)
aa246-274
(7)
aa600-850
(4)
CD11c
(2)
Internal
(2)
aa1-168
(1)
aa20-1116
(1)
Publications
No
(161)
Yes
(1)
Tag
GST, N-terminus
(1)
His-GST
(1)
His-T7
(1)
MBP, N-terminus + 6His, C-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Human
(3)
Mouse
(2)
Source
293T Cells
(1)
Baculovirus
(1)
E. coli
(2)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(1)
Cancer
Fast Shipping
ITGAX / CD11c Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
Cancer
Fast Shipping
ITGAX / CD11c Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
ITGAX / CD11c Rabbit anti-Human Polyclonal (aa1119-1145) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ITGAX / CD11c Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$328; 100 µl/$419
ITGAX / CD11c Hamster anti-Mouse Monoclonal (N418) Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$562; 250 µg/$763
ITGAX / CD11c Hamster anti-Mouse Monoclonal (Biotin) Antibody
Mouse
Flo, IF, IHC, IP
Biotin Conjugated
100 µl/$860
Cancer
ITGAX / CD11c Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$460
ITGAX / CD11c Mouse anti-Human Monoclonal (3.9) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
25 µg/$249; 100 µg/$279
ITGAX / CD11c Mouse anti-Human Monoclonal (aa600-850) (Azide-free, BSA-free) (ITGAX/1242) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
E. coli
His-GST
53.9 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
ITGAX / CD11c Hamster-Armenian anti-Mouse Monoclonal (N418) Antibody
Mouse
Flo, IHC, IHC-Pfa, IP
Unconjugated
50 µg/$445; 500 µg/$577
ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITGAX / CD11c Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$558
ITGAX / CD11c Rabbit anti-Mouse Polyclonal (aa907-1115) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ITGAX / CD11c Mouse anti-Human Monoclonal (FITC) (3.9) Antibody
Human
Flo
FITC Conjugated
25 Tests/$285; 100 Tests/$352
ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ITGAX / CD11c Mouse anti-Human Monoclonal (HC1/1) Antibody
Human
Block, Flo, Func, IF, IHC, IHC-Fr
Unconjugated
20 µg/$371; 100 µg/$574
ITGAX / CD11c Hamster-Armenian anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (N418) Antibody
Mouse
Flo, IF, IHC, IP
Unconjugated, Azide-free, Low Endotoxin
50 µg/$271
ITGAX / CD11c Mouse anti-Human Monoclonal (6G2D1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITGAX / CD11c Rat anti-Mouse Monoclonal (223H7) Antibody
Mouse
Flo, IP
Unconjugated
100 µg/$370
ITGAX / CD11c Mouse anti-Human Monoclonal (Preservative Free) (CBR-p150/4G1) Antibody
Human
Flo, IHC-Fr
Unconjugated, Preservative Free
0.1 mg/$597
ITGAX / CD11c Mouse anti-Dog Monoclonal (Supernatant) (CA11.6A1) Antibody
Dog
Flo, IHC-Fr, IP
Unconjugated, Supernatant
2 ml/$509
ITGAX / CD11c Mouse anti-Human Monoclonal (FITC) (BU15) Antibody
Human, Monkey
Flo, IHC-Fr, IP
FITC Conjugated
100 Tests/$337
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of 162
product results
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