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Anti-ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV-7, RPE) LS-C57971

Note: This antibody replaces LS-C57972

Ordering

Wt. Vol. Conc. Price
- 100 tst - $655
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ITGAV/Integrin Alpha V/CD51 Antibodies

Anti-ITGAV/Integrin Alpha V/CD51 Antibody IHC-plus™ LS-B6866
Mouse Monoclonal (IgG1) to Human ITGAV/Integrin Alpha V/CD51
Human
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated
Immunohistochemistry Image
Anti-ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV-7) LS-C57970
Rat Monoclonal [clone RMV-7] (IgG1) to Mouse ITGAV/Integrin Alpha V/CD51
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-ITGAV/Integrin Alpha V/CD51 Antibody (aa840-889) IHC-plus™ LS-B5254
Rabbit Polyclonal (IgG) to Human ITGAV/Integrin Alpha V/CD51
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone RMV-7] (IgG1) to Mouse ITGAV/Integrin Alpha V/CD51
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
RPE Conjugated

Details

Mouse ITGAV/Integrin Alpha V/CD51
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [RMV-7]
R. Phycoerythrin. Also available Unconjugated.
Affinity purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:10)
  • (applications tested for the base form of this product only)

Specificity and Use

ITGAV/Integrin Alpha V/CD51 antibody was raised against cultured LAK cells from Balb/c mice.
Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
+4°C, avoid freezing
For research use only.

About ITGAV/Integrin Alpha V/CD51

P06756 NM_002210 NP_002201.1

ITGAV Antibody, CD51 Antibody, CD51 antigen Antibody, Integrin, alpha V Antibody, MSK8 Antibody, Integrin Alpha V Antibody, Integrin alpha-V Antibody, VNRA Antibody, Vitronectin receptor Antibody, Integrin alphaVbeta3 Antibody, VTNR Antibody

ITGAV/Integrin Alpha V/CD51 is a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins.

Requested From: United States
Date Requested: 12/7/2016

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