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ITGAM / CD11b Antibody (clone OX‑42) LS‑C96404 Best Seller
Antibody
CD11b antibody LS-C96404 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for IHC.
Catalog
Size
Price
LS-C96404-1000
1000 µg (1 mg/ml)
Unavailable

Popular ITGAM / CD11b Products

Antibody
Species: Mouse
Applications: IHC, IHC - Paraffin, IHC - Frozen, Flow Cytometry
Anti-CD11b antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3760 concentration 10 ug/ml.
Species: Mouse, Human, Rabbit
Applications: IHC, IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Antibody
Species: Bovine, Goat, Sheep
Applications: Flow Cytometry
CD11b Antibody - Microglia Marker - IHC of CD11b in human renal cancer using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin

Product Description

CD11b antibody LS-C96404 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for IHC.
About ITGAM / CD11b
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. P11215 NM_000632 NP_000623.2

ITGAM Antibody, Antigen CD11b (p170) Antibody, CD11B Antibody, CD11b antigen Antibody, CR3A Antibody, Integrin alpha-M Antibody, MAC-1 Antibody, MO1A Antibody, Neutrophil adherence receptor Antibody, MAC1A Antibody, SLEB6 Antibody, CR-3 alpha chain Antibody


Specifications

Target
ITGAM / CD11b
Host
Mouse
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
Monoclonal [OX-42]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:100 - 1:200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ITGAM / CD11b antibody was raised against peritoneal macrophages
Specificity
CD11b/c. OX-42 recognizes three major polypeptides of 160kDa, 103kDa and 95kDa and a minor 133kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163kDa and 100kDa and a minor 135kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested
Presentation
PBS pH 7.2, 0.09% sodium azide
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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