Dog ITGAM / CD11b

Mouse

Dog (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

CA16.3E10

Unconjugated

Tissue culture supernatant

Supernatant

Affinity purified beta-2 integrins from splenic lysate.

Is a monoclonal antibody recognizing the canine CD11b cell surface antigen, a member of the alpha integrin family. CD11b forms one of the possible alpha chains of the canine leukocyte adhesion complexes (LeuCAMs), these contain a common 95 kD beta chain non-covalently bound to either a 150 kD, 165 kD (CD11b) or 180 kD (CD11a) alpha chain. The CD11/CD18 complex is also known as the CR3 receptor. Canine CD11b is expressed by granulocytes, monocytes, NK cells and some macrophages. Has been used to evaluate the effect of anesthetic administration of CD11b expression on canine neutrophils demonstrating attenuation of CD11b expression at high concentrations administered lidocaine hydrochloride and reduced adhesion of neutrophils to endothelium.

• IHC - Frozen
• Immunoprecipitation
• Flow Cytometry (1:1)

• IHC - Paraffin

PBS, 0.1% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P11215 NCBI: NM_000632 NP_000623.2