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Anti-ITGAM / CD11b Antibody (clone 5C6) LS-C188733


Wt. Vol. Conc. Price
1000 µg - 1 mg/ml $705
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ITGAM / CD11b Antibodies

Anti-ITGAM / CD11b Antibody (clone M1/70.15) IHC-plus™ LS-B3760
Rat Monoclonal [clone M1/70.15] (IgG2b) to Mouse ITGAM / CD11b
Mouse, Human, Rabbit
IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image
Anti-ITGAM / CD11b Antibody (FITC) LS-C127442
Mouse Monoclonal (IgG2b) to Bovine ITGAM / CD11b
Bovine, Goat, Sheep
Flow Cytometry
FITC Conjugated
Anti-ITGAM / CD11b Antibody (Internal) LS-C141892
Rabbit Polyclonal to Mouse ITGAM / CD11b
Mouse, Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 5C6] (IgG2b) to Mouse ITGAM / CD11b
Mouse, Human
IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry


Mouse ITGAM / CD11b
Mouse, Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [5C6]
Protein G purified


  • IHC - Frozen
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry (1:100)

Specificity and Use

ITGAM / CD11b antibody was raised against thioglycollate-elicited Peritoneal Macrophages (TPM).
Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.


PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About ITGAM / CD11b

P11215 NM_000632 NP_000623.2

ITGAM Antibody, Antigen CD11b (p170) Antibody, CD11B Antibody, CD11b antigen Antibody, CR3A Antibody, Integrin alpha-M Antibody, MAC-1 Antibody, MO1A Antibody, Neutrophil adherence receptor Antibody, MAC1A Antibody, SLEB6 Antibody, CR-3 alpha chain Antibody

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Requested From: United States
Date Requested: 10/27/2016

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