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Anti-ITGAM / CD11b Antibody (Biotin) LS-C45329

Note: This antibody replaces LS-C58656


Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $225
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ITGAM / CD11b Antibodies

Anti-ITGAM / CD11b Antibody (clone M1/70.15) IHC-plus™ LS-B3760
Rat Monoclonal [clone M1/70.15] (IgG2b) to Mouse ITGAM / CD11b
Mouse, Human, Rabbit
IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image
Anti-ITGAM / CD11b Antibody (FITC) LS-C127442
Mouse Monoclonal (IgG2b) to Bovine ITGAM / CD11b
Bovine, Goat, Sheep
Flow Cytometry
FITC Conjugated
Anti-ITGAM / CD11b Antibody (Internal) LS-C141892
Rabbit Polyclonal to Mouse ITGAM / CD11b
Mouse, Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse ITGAM / CD11b
Mouse, Human, Rabbit
Flow Cytometry
Biotin Conjugated


Mouse ITGAM / CD11b
Mouse, Human, Rabbit (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Protein G purified


Flow Cytometry (1:1)

Specificity and Use

ITGAM / CD11b antibody was raised against t cell enriched splenocytes from B10 mice.
Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. * Clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.


0.09% sodium azide, 1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ITGAM / CD11b

P11215 NM_000632 NP_000623.2

ITGAM Antibody, Antigen CD11b (p170) Antibody, CD11B Antibody, CD11b antigen Antibody, CR3A Antibody, Integrin alpha-M Antibody, MAC-1 Antibody, MO1A Antibody, Neutrophil adherence receptor Antibody, MAC1A Antibody, SLEB6 Antibody, CR-3 alpha chain Antibody

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Requested From: United States
Date Requested: 10/23/2016

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