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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGAL / CD11a Antibody (RPE) LS‑C43517
Note: This antibody replaces LS-C57324
Antibody
CD11a antibody LS-C43517 is an RPE-conjugated rat monoclonal antibody to mouse CD11a (ITGAL). Validated for Flow and IP.
Catalog
Size
Price
LS-C43517-100
100 tst
Unavailable

Popular ITGAL / CD11a Products

Human peripheral blood lymphocytes stained with purified HI111, followed by anti-mouse IgGs FITC
Species: Human, Baboon, Monkey, Bovine, Cat, Dog, Rabbit, Sheep
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry, Blocking, Functional Assay, Neutralization
Flow cytometry of LFA-1 / CD11a antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot, Flow Cytometry, Functional Assay
Anti-ITGAL / CD11a antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5915 concentration 3.75 ug/ml.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: Flow Cytometry

Product Description

CD11a antibody LS-C43517 is an RPE-conjugated rat monoclonal antibody to mouse CD11a (ITGAL). Validated for Flow and IP.
About ITGAL / CD11a
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. P20701 NM_002209 NP_002200.2

ITGAL Antibody, CD11A Antibody, Integrin alpha-L Antibody, LFA-1 alpha Antibody, LFA-1A Antibody, Integrin gene promoter Antibody, Alpha polypeptide) Antibody, CD11a antigen Antibody, LFA-1 Antibody, LFA1A Antibody


Specifications

Target
Mouse ITGAL / CD11a
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
R. Phycoerythrin. Also available Unconjugated or conjugated with FITC.
Purification
Purified
Modifications
Unmodified
Applications
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:2)
  • (applications tested for the base form of this product only)
Immunogen
ITGAL / CD11a antibody was raised against whole BW5147 cells.
Specificity
Recognizes murine CD11a, a ~170-180kD type I membrane glycoprotein, also known as the integrin alpha L subunit. CD11a is a member of the integrin family of adhesion molecules. CD11a is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes. Is reported to block the cytolytic activity of cytotoxic T cell lines.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Presentation
Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Reconstitution
100 tst Distilled Water.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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