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Catalog Number Size Price
LS-C188546-0.1 0.1 mg (0.5 mg/ml) $373 
Antibody

Monoclonal Hamster anti‑Mouse ITGAE / CD103 Antibody (clone 2E7, IHC, IF) LS‑C188546

Monoclonal Hamster anti‑Mouse ITGAE / CD103 Antibody (clone 2E7, IHC, IF) LS‑C188546

Antibody:
ITGAE / CD103 Hamster anti-Mouse Monoclonal (2E7) Antibody
Application:
IHC-Fr, IF, IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$373
LS-C188546-0.1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ITGAE / CD103 Hamster anti-Mouse Monoclonal (2E7) Antibody
Application:
IHC-Fr, IF, IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
CD103 antibody LS-C188546 is an unconjugated hamster monoclonal antibody to mouse CD103 (ITGAE). Validated for Flow, IF, IHC and IP.
Target
Mouse ITGAE / CD103
Synonyms
ITGAE | CD103 | CD103 antigen | Integrin alpha-E | HML-1 antigen | Integrin alpha-IEL | Alpha polypeptide) | Mucosal lymphocyte 1 antigen | HUMINAE
Host
Hamster
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Clone
2E7
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Mouse intestinal intraepithelial lymphocytes.
Specificity
Recognizes mouse CD103, otherwise known as Integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule aE7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The aE7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells. Clone 2E7 has been reported to also recognize the aE7 complex.
Applications
  • IHC - Frozen
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:20)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Tested in IF only with frozen sections fixed in acetone.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGAE / CD103
P38570 NM_002208 NP_002199.3

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/19/2024