Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

ITGA8 / Integrin Alpha 8

integrin, alpha 8

Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: integrin, alpha 8
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA8, Integrin, alpha 8, Integrin alpha-8
Target Sequences: L36531 AAA93514.1 P53708

Publications (2)

1
Robust isolation of malignant plasma cells in multiple myeloma. Frigyesi I, Adolfsson J, Ali M, Christophersen MK, Johnsson E, Turesson I, Gullberg U, Hansson M, Nilsson B. Blood. 2014 123:1336-40. (Flo; Human) [Full Text Article] [PubMed:24385542] Related Antibodies: LS-C130071.
2
An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells. Qing Chen, Peishun Shou, Liying Zhang, Chunliang Xu, Chunxing Zheng, Yanyan Han, Wenzhao Li, Yin Huang, Xiaoren Zhang, Changshun Shao, Arthur I Roberts, Arnold B Rabson, Guangwen Ren, Yanyun Zhang, Ying Wang, David T Denhardt, Yufang Shi. Stem cells (Dayton, Ohio). 2014 February;32:327-37. [Full Text Article] [PubMed:24123709] [PMC:PMC3961005] Related Antibodies: LS-C36922.

☰ Filters
Antibodies (35)
Proteins (5)
Over-Expression Lysate (2)
Primary (35)
Recombinant (3)
ITGA8 / Integrin Alpha 8 (40)
Human (33)
Mouse (11)
Rat (7)
Chimpanzee (3)
Dog (3)
Monkey (1)
Pig (3)
Zebrafish (3)
IHC (8)
IHC-P (1)
WB (32)
Flo (2)
ELISA (13)
ICC (2)
Peptide-ELISA (1)
rabbit (25)
mouse (8)
goat (2)
IgG (12)
IgG2b (2)
IgG2b,k (6)
monoclonal mc (8)
polyclonal pc (27)
APC (1)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (12)
aa907-1063 (8)
aa1025-1053 (7)
aa251-300 (4)
aa610-800 (2)
C-Terminus (1)
aa38-1007 (1)
aa836-936 (1)
No (38)
Yes (2)
GST, N-terminus (1)
His-GST-S (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Select
ITGA8 / Integrin Alpha 8 Goat anti-Mouse Polyclonal (aa38-1007) Antibody
Mouse
ICC, WB
Unconjugated
100 µg/$962
Select
ITGA8 / Integrin Alpha 8 Goat anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ICC, WB
Biotin Conjugated
50 µg/$1,043
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (aa610-800) (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$907
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ITGA8 / Integrin Alpha 8 Antibody - ITGA8 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa1025-1053) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ITGA8 / Integrin Alpha 8 Antibody - Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using ITGA8 Polyclonal Antibody at dilution of 1:30(×200)
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (aa836-936) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ITGA8 / Integrin Alpha 8 Antibody - Western blot analysis ITGA8 using LOVO cells whole cells lysates
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ITGA8 / Integrin Alpha 8 Mouse anti-Human Monoclonal (aa610-800) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$824
ITGA8 / Integrin Alpha 8 Antibody - ITGA8 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
WB
Unconjugated
100 µl/$424
ITGA8 / Integrin Alpha 8 Antibody - ITGA8 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa251-300) (FITC) Antibody
Zebrafish, Mouse, Dog, Rat, Pig, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ITGA8 / Integrin Alpha 8 Antibody - Western blot analysis of Integrin alpha 8 HC expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ITGA8 / Integrin Alpha 8 Antibody - Western blot of ITGA8 / Integrin Alpha 8 antibody.
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal (aa907-1063) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
ITGA8 / Integrin Alpha 8 Antibody - Western blot analysis of extracts of various cell lines, using ITGA8 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
ITGA8 / Integrin Alpha 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 40 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).