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Anti-ITGA6/Integrin Alpha 6/CD49f Antibody (clone GoH3) LS-C41344

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $225
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Most Popular ITGA6/Integrin Alpha 6/CD49f Antibodies

Anti-ITGA6/Integrin Alpha 6/CD49f Antibody (Internal) IHC-plus™ LS-A8768
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGA6/Integrin Alpha 6/CD49f Antibody (N-Terminus) IHC-plus™ LS-A8770
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGA6/Integrin Alpha 6/CD49f Antibody IHC-plus™ LS-B11070
Mouse Monoclonal (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (7)
Rat Monoclonal [clone GoH3] (IgG2a) to Human ITGA6/Integrin Alpha 6/CD49f
Human, Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Human ITGA6/Integrin Alpha 6/CD49f
Rat
Human, Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [GoH3]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry

  • IHC - Paraffin

Specificity and Use

ITGA6/Integrin Alpha 6/CD49f antibody was raised against cells.
ITGA6/CD49f from mouse and human

Packaging

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
+4°C. Store undiluted.
For research use only.

Publications (7)

1
Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. Stepp MA, Liu Y, Pal-Ghosh S, Jurjus RA, Tadvalkar G, Sekaran A, Losicco K, Jiang L, Larsen M, Li L, Yuspa SH. Journal of cell science. 2007 120:2851-63. [PubMed:17666434]
2
Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5774-9. (IHC) [PubMed:18391223] [PMC:PMC2311360]
3
Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Science signaling. 2009 2:ra2. [PubMed:19176516] [PMC:PMC2906144]
4
Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Xu T, Xu Y, Liao CP, Lau R, Goldkorn A. Molecular cancer therapeutics. 2010 9:438-49. [PubMed:20124445] [PMC:PMC2820598]
5
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL. Cancer research. 2010 70:8948-58. [PubMed:20940399] [PMC:PMC2970644]
6
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus MC, Tetta C, Bussolati B, Camussi G. Cancer research. 2011 71:5346-56. [PubMed:21670082]
7
Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Lai KP, Yamashita S, Vitkus S, Shyr CR, Yeh S, Chang C. Molecular endocrinology (Baltimore, Md.). 2012 26:52-66. [PubMed:22135068] [PMC:PMC3248327]
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About ITGA6/Integrin Alpha 6/CD49f

P23229 NM_000210 NP_000201.2

ITGA6 Antibody, CD49f Antibody, CD49f antigen Antibody, Integrin alpha6B Antibody, Integrin, alpha 6 Antibody, Integrin alpha-6 precursor Antibody, VLA-6 Antibody, Integrin alpha-6 Antibody, ITGA6B Antibody

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Immunohistochemistry

Immunohistochemistry
MDA-MB-231 breast cancer cells were stained with anti-CD49f (clone GoH3) followed by DyLight 649 Goat anti-rat Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.

Flow Cytometry

Flow Cytometry
Human peripheral blood lymphocytes stained with purified GoH3, followed by anti-rat IgGs FITC

Requested From: United States
Date Requested: 12/11/2016

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