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Anti-ITGA5/Integrin Alpha 5/CD49e Antibody (PE) LS-C13680

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Mouse Monoclonal (IgG2b) to Human ITGA5/Integrin Alpha 5/CD49e
Human
Immunofluorescence, Flow Cytometry, Functional Assay
PE Conjugated

Details

Human ITGA5/Integrin Alpha 5/CD49e
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Phycoerythrin
Ion exchange chromatography

Applications

Immunofluorescence, Flow Cytometry, Functional Assay

Specificity and Use

ITGA5/Integrin Alpha 5/CD49e antibody was raised against u937 cells.
Directed against the CD49e antigen (GPIc or VLA-5 alpha chain), which can form distinct complexes with either the CD29 antigen (GP IIa or VLA beta chain), resulting in the VLA-5 (alpha 5 beta 1) complex which is expressed on human platelets. Reacts with platelets and monocytes and also weakly with T-cells and granulocytes. It also reacts with various cell types of non-hemopoietic origin.
Suitable for use in Immunofluorescence, Flow Cytometry and Functional Studies. Flow Cytometry: 10 ul per test.

Packaging

PBS, 10 mM sodium azide,1 mg/ml BSA.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About ITGA5/Integrin Alpha 5/CD49e

P08648 NM_002205 NP_002196.2

ITGA5 Antibody, FNRA Antibody, Integrin alpha-5 Antibody, Integrin Alpha 5 Antibody, Integrin alpha-F Antibody, VLA-5 Antibody, CD49e Antibody, CD49e antigen Antibody, VLA5A Antibody

ITGA5/Integrin Alpha 5/CD49e belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Requested From: United States
Date Requested: 9/30/2016

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