Target
Mouse ITGA5/Integrin Alpha 5/CD49e
Synonyms
ITGA5 | FNRA | Integrin alpha-5 | Integrin Alpha 5 | Integrin alpha-F | VLA-5 | CD49e | CD49e antigen | VLA5A
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Conjugations
FITC.
Also available
Unconjugated.
Purification
Protein G purified
Immunogen
Mouse MC/9 cell line.
Specificity
Recognizes murine integrin alpha 5 (CD49e), which associates with the beta 1 integrin (CD29) to form the fibronectin receptor CD49e/CD29 (VLA-5). VLA-5 plays an important role in cell adhesion and migration and is expressed by mast cells, thymocytes, T-cells and monocytes. Clone MFR5(5H10) has been reported to block CD49e mediated function. XXX recommend the use of MCA2296EL for this purpose.
Applications
- Flow Cytometry (1:1)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100ml. Method sheets are available on request. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Presentation
PBS, 0.09% Sodium Azide, 1% BSA
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGA5/Integrin Alpha 5/CD49e