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Anti-ITGA4 / VLA-4 / CD49d Antibody LS-C13656

Ordering

Wt. Vol. Conc. Price
100 µg - - $545
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Mouse Monoclonal (IgG1) to Human ITGA4 / VLA-4 / CD49d
Human, Monkey, Rat, Pig
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Human ITGA4 / VLA-4 / CD49d
Mouse
Human, Monkey, Rat, Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Purified

Applications

IHC - Frozen, Immunoprecipitation, Flow Cytometry

Specificity and Use

ITGA4 / VLA-4 / CD49d antibody was raised against jM leukemia line.
Recognizes the 80kD alpha chain of VLA-4. Reacts with monocytes, T-cells, B cells, thymocytes and Langerhans cells. Can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure. HP2/1 inhibits cell binding to soluble VCAM-1. Species cross-reactivity: Rat, porcine, rhesus monkey.
Flow cytometry: 1 ug/5 X 10^5 cells. Immunohistochemistry on frozen tissue sections. Immunoprecipitation.

Packaging

PBS, pH 7.2, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ITGA4 / VLA-4 / CD49d

P13612 NM_000885 NP_000876.3

ITGA4 Antibody, 269C wild type Antibody, CD49D Antibody, IA4 Antibody, Integrin alpha-4 Antibody, Integrin alpha 4 Antibody, Integrin alpha-4 subunit Antibody, Integrin alpha-IV Antibody, VLA-4 Antibody, VLA-4 subunit alpha Antibody, CD49d antigen Antibody

ITGA4 encodes integrin alpha chain 4. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Although alpha 4 is variably cleaved to yield two unlinked chains, this cleavage is unnecessary for integrin assembly and function.

Requested From: United States
Date Requested: 9/26/2016

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