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Anti-ITGA4 / VLA-4 / CD49d Antibody (clone 9F10) LS-C40971

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $215
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ITGA4 / VLA-4 / CD49d Antibodies

Anti-ITGA4 / VLA-4 / CD49d Antibody (C-Terminus) IHC-plus™ LS-A9388
Rabbit Polyclonal to Human ITGA4 / VLA-4 / CD49d
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGA4 / VLA-4 / CD49d Antibody (Internal) IHC-plus™ LS-B3837
Rabbit Polyclonal to Human ITGA4 / VLA-4 / CD49d
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ITGA4 / VLA-4 / CD49d Antibody (clone PS/2, Azide-free, Low Endotoxin) LS-C149732
Rat Monoclonal [clone PS/2] (IgG2b,k)
Human, Mouse
IHC - Frozen, Flow Cytometry, Inhibition
Unconjugated, Azide-free, Low Endotoxin

100% Guaranteed 100% Guaranteed Publications Publications (3)
Mouse Monoclonal [clone 9F10] (IgG1) to Human ITGA4 / VLA-4 / CD49d
Human, Baboon, Monkey, Bovine, Cat, Dog, Horse, Sheep
IHC - Frozen, Flow Cytometry
Unconjugated

Details

Human ITGA4 / VLA-4 / CD49d
Mouse
Human, Baboon, Monkey, Bovine, Cat, Dog, Horse, Sheep (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [9F10]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Frozen
  • Flow Cytometry

  • IHC - Paraffin

Specificity and Use

Packaging

PBS, pH 7.2, 0.09% sodium azide.
+4°C, avoid freezing
For research use only.

Publications (3)

1
CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells. Kleinewietfeld M, Starke M, Di Mitri D, Borsellino G, Battistini L, Rtzschke O, Falk K. Blood. 2009 113:827-36. [PubMed:18941119]
2
High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease. Palacios F, Moreno P, Morande P, Abreu C, Correa A, Porro V, Landoni AI, Gabus R, Giordano M, Dighiero G, Pritsch O, Oppezzo P. Blood. 2010 115:4488-96. [PubMed:20233972]
3
Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells. Mattapallil MJ, Silver PB, Mattapallil JJ, Horai R, Karabekian Z, McDowell JH, Chan CC, James EA, Kwok WW, Sen HN, Nussenblatt RB, David CS, Caspi RR. Journal of immunology (Baltimore, Md. : 1950). 2011 187:1977-85. [PubMed:21765017] [PMC:PMC3150271]

About ITGA4 / VLA-4 / CD49d

P13612 NM_000885 NP_000876.3

ITGA4 Antibody, 269C wild type Antibody, CD49D Antibody, IA4 Antibody, Integrin alpha-4 Antibody, Integrin alpha 4 Antibody, Integrin alpha-4 subunit Antibody, Integrin alpha-IV Antibody, VLA-4 Antibody, VLA-4 subunit alpha Antibody, CD49d antigen Antibody

ITGA4 encodes integrin alpha chain 4. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Although alpha 4 is variably cleaved to yield two unlinked chains, this cleavage is unnecessary for integrin assembly and function.

Flow Cytometry

Flow Cytometry
Human peripheral blood lymphocytes stained with purified 9F10, followed by anti-mouse IgGs FITC
 

Requested From: United States
Date Requested: 12/2/2016

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