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| Catalog Number | Size | Price |
|---|---|---|
| LS-C44593-0.1 | 0.1 mg | $373 |
Monoclonal Rat anti‑Mouse ITGA4 / VLA‑4 / CD49d Antibody (clone 9C10 (MFR.4.B), IHC) LS‑C44593
Monoclonal Rat anti‑Mouse ITGA4 / VLA‑4 / CD49d Antibody (clone 9C10 (MFR.4.B), IHC) LS‑C44593
Note: This antibody replaces LS-C57842, LS-C44590, LS-C13671
Antibody:
ITGA4 / VLA-4 / CD49d Rat anti-Mouse Monoclonal (9C10 (MFR.4.B)) Antibody
Application:
IHC-Fr, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ITGA4 / VLA-4 / CD49d Rat anti-Mouse Monoclonal (9C10 (MFR.4.B)) Antibody
Application:
IHC-Fr, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
CD49d antibody LS-C44593 is an unconjugated rat monoclonal antibody to mouse CD49d (ITGA4 / VLA-4). Validated for Flow and IHC.
Target
Mouse ITGA4 / VLA-4 / CD49d
Synonyms
ITGA4 | 269C wild type | CD49D | IA4 | Integrin alpha-4 | Integrin alpha 4 | Integrin alpha-4 subunit | Integrin alpha-IV | VLA-4 | VLA-4 subunit alpha | CD49d antigen
Host
Rat
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Clone
9C10 (MFR.4.B)
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Mouse LyD9 hematopoietic progenitor cells.
Specificity
Recognizes murine alpha 4 integrin (CD49d), a 150kD glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1. Clone 9C10 (MFR4. B) is reported to significantly inhibit binding of CD49d to CD106 but only when used in combination with clone R1-2. Removal of sodium azide is recommended prior to use in functional assays - XXX recommend the use of EQU003 for this purpose.
Applications
- IHC - Frozen
- Flow Cytometry (1:10)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGA4 / VLA-4 / CD49d
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
