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Anti-ITGA3 / CD49c Antibody LS-C13622

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $545
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Most Popular ITGA3 / CD49c Antibodies

Anti-ITGA3 / CD49c Antibody (aa1040-1051) LS-C15959
Rabbit Polyclonal (IgG) to Human ITGA3 / CD49c
Human
IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation, ELISA, Radioimmunoassay
Unconjugated
Anti-ITGA3 / CD49c Antibody (N-Terminus) IHC-plus™ LS-A8136
Rabbit Polyclonal to Human ITGA3 / CD49c
Human, Bovine
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGA3 / CD49c Antibody (Internal) IHC-plus™ LS-A8140
Rabbit Polyclonal to Human ITGA3 / CD49c
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1,k) to Human ITGA3 / CD49c
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated

Details

Human ITGA3 / CD49c
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry
  • Functional Assay

Specificity and Use

ITGA3 / CD49c antibody was raised against human squamous cell carcinoma cells (SCC9).
Recognized human a3 integrin (CD49c).
Suitable for use in Inhibition of Cell Attachment, Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Inhibition of Cell Attachment: Inhibits SCC9 cell adhesion to human and EHS laminin, and laminin GD-2 peptide. Potentiates inhibition of SKOV-3 cell adhesion to EHS laminin by anti-integrin alpha 5 antibody GoH3. Does not inhibit cell adhesion to fibronectin or collagen type IV. Flow Cytometry: Stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC). Immunohistochemistry: On acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue. Immunoprecipitation: Precipitates PAGE bands of 130kD (reduced) or 116kD and 135kD (non-reduced) from surface-biotinylated SCC9 or SKOV-3 cells.

Packaging

PBS, pH 7.6, 0.1% sodium azide.
Short term: 4º C, Long term: aliquot to avoid repeated freezing and thawing, and store at -20º C.
For research use only.

About ITGA3 / CD49c

P26006 NM_002204 NP_002195.1

ITGA3 Antibody, Alpha3 integrin Antibody, CD49c antigen Antibody, CD49C Antibody, GAPB3 Antibody, Integrin alpha-3 Antibody, FRP-2 Antibody, VCA-2 Antibody, VLA-3 subunit alpha Antibody, VL3A Antibody, VLA3a Antibody, Galactoprotein B3 Antibody, GAP-B3 Antibody, ILNEB Antibody, Integrin alpha3 Antibody, MSK18 Antibody

ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins.

Requested From: United States
Date Requested: 12/5/2016

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