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ITGA2B / CD41
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
| Gene Name: | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA |
| Target Sequences: | NM_000419 NP_000410.2 P08514 |
Publications (1)
1
Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions. Xiaoman Zhang, Toshihide Takeuchi, Akiko Takeda, Hideki Mochizuki, Yoshitaka Nagai. PloS one. 2022 June;17:e0270634. [Full Text Article]
[PubMed:35749554]
[PMC:PMC9231772]
Related Antibodies: LS-B13882.
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ITGA2B / CD41 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ITGA2B / CD41 Rabbit anti-Human Polyclonal (aa122-171) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ITGA2B / CD41 Rabbit anti-Human Polyclonal (aa122-171) (HRP) Antibody
Mouse, Dog, Guinea pig, Rat, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ITGA2B / CD41 Rabbit anti-Human Polyclonal (aa122-171) (FITC) Antibody
Mouse, Dog, Guinea pig, Rat, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ITGA2B / CD41 Rat anti-Mouse Monoclonal (MWReg30) Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$385
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
ITGA2B / CD41 Rabbit anti-Human Polyclonal (aa677-711) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ITGA2B / CD41 Mouse anti-Human Monoclonal (HIP8) Antibody
Human, Monkey, Baboon
Flo, IHC, IHC-Fr
Unconjugated
100 µg/$277
ITGA2B / CD41 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
ITGA2B / CD41 Rabbit anti-Human Polyclonal (aa210-532) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
Sandwich
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ITGA2B / CD41 Rabbit anti-Rabbit Recombinant Monoclonal (7E3) Antibody
Rabbit, Human
Block, Flo
Unconjugated
0.2 mg/$540
ITGA2B / CD41 Rat anti-Mouse Monoclonal (FITC) Antibody
Mouse
Flo
FITC Conjugated
100 µg/$672
ITGA2B / CD41 Mouse anti-Human Monoclonal (RPE) (PM6/248) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
ITGA2B / CD41 Rat anti-Mouse Monoclonal (386629) Antibody
Mouse
ELISA, Flo, ICC, IHC, IHC-Fr
Unconjugated
100 µg/$896
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
ITGA2B / CD41 Mouse anti-Human Monoclonal (HIP2) Antibody
Human, Non-Human Primates
Flo, IHC, IHC-Fr
Unconjugated
0.1 mg/$309
ITGA2B / CD41 Mouse anti-Human Monoclonal (Gi5) Antibody
Human
Flo, ICC, IP
Unconjugated
100 µg/$605
ITGA2B / CD41 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$896
ITGA2B / CD41 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$657
ITGA2B / CD41 Mouse anti-Human Monoclonal (Azide-free) (96.2C1) Antibody
Human
Flo
Unconjugated, Azide-free
100 µg/$411
ITGA2B / CD41 Mouse anti-Human Monoclonal (aa45-149) (2E10C9) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
ITGA2B / CD41 Mouse anti-Human Monoclonal (aa45-149) (2E10C9) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
ITGA2B / CD41 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$657
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