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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGA2B / CD41 Antibody (clone MM2/356) LS‑C188536
CD41 antibody LS-C188536 is an unconjugated mouse monoclonal antibody to CD41 (ITGA2B) from human, mink, mustelid and other species. Validated for Flow and IP.
Catalog
Size
Price
LS-C188536-2000
2000 µl (0.01 mg/ml)
Unavailable

Popular ITGA2B / CD41 Products

Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
IHC of paraffin-embedded PC13 xenograft using Integrin alpha 2b antibody at 1:500 dilution.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-ITGA2B  / CD41 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9763 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Dog, Guinea pig
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CD41 antibody LS-C188536 is an unconjugated mouse monoclonal antibody to CD41 (ITGA2B) from human, mink, mustelid and other species. Validated for Flow and IP.
About ITGA2B / CD41
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. P08514 NM_000419 NP_000410.2

ITGA2B Antibody, BDPLT2 Antibody, CD41B Antibody, GT Antibody, gp2B Antibody, Integrin alpha-IIb Antibody, ITGAB Antibody, GPIIb Antibody, HPA3 Antibody, Platelet-specific antigen BAK Antibody, CD41 Antibody, CD41 antigen Antibody, GPalpha IIb Antibody, GTA Antibody


Specifications

Target
Human ITGA2B / CD41
Host
Mouse
Reactivity
Human, Mink, Pig, Mustelid (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [MM2/356]
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • Immunoprecipitation
  • Flow Cytometry (1:1)
Immunogen
ITGA2B / CD41 antibody was raised against human Platelet membranes.
Specificity
Recognizes human CD41, a cell surface antigen which is expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb.
Presentation
Tissue culture supernatant, Tris buffered saline, 0.09% sodium azide
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41
Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41

Flow Cytometry

Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41
Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41

Flow Cytometry

Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41
Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41

Flow Cytometry

Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41
Flow cytometry of human peripheral blood platelets with Mouse anti-Human CD41


Requested From: 
Date Requested: 6/23/2018

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