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Anti-ITGA2B / CD41 Antibody (clone CLB-48) LS-C127668

Ordering

Wt. Vol. Conc. Price
- 1000 µl 0.1 mg/ml $995
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular ITGA2B / CD41 Antibodies

Anti-ITGA2B / CD41 Antibody LS-C13305
Mouse Monoclonal (IgG2a) to Human ITGA2B / CD41
Human
Flow Cytometry
Unconjugated
Anti-ITGA2B / CD41 Antibody (aa210-532) LS-C186328
Rabbit Polyclonal (IgG) to Human ITGA2B / CD41
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ITGA2B / CD41 Antibody (aa122-171) IHC-plus™ LS-B9763
Rabbit Polyclonal to Human ITGA2B / CD41
Human, Mouse, Rat, Dog, Guinea pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone CLB-48] (IgG1) to Human ITGA2B / CD41
Human
Immunofluorescence, Flow Cytometry
Unconjugated

Details

Human ITGA2B / CD41
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CLB-48]
Unconjugated
Ion exchange chromatography
Unmodified

Applications

  • Immunofluorescence
  • Flow Cytometry

Specificity and Use

ITGA2B / CD41 antibody was raised against human platelets.
Recognizes human CD41. Reacts with the intact platelet GPIIb/IIIa complex. Does not bind to dissociated GPIIb or GPIIIa. Recognizes human thrombocytes and megakaryocytes. Does not bind to platelets from patients with Glanzmann thrombasthenia and does not recognize the vitronectin receptor, which contains GPIIa as a beta subunit (cf. CD61). Activates human thrombocytes and induces thrombocyte aggregation in the absence of thrombocyte inhibitors such as EDTA.
Suitable for use in Indirect Immunofluorescence, Flow Cytometry and Fluorescence Microscopy.

Packaging

20 mM Tris, 150 mM sodium chloride, pH 8.0, 10 mg BSA, 0.001% Merthiolate
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.
For research use only.

About ITGA2B / CD41

P08514 NM_000419 NP_000410.2

ITGA2B Antibody, BDPLT2 Antibody, CD41B Antibody, GT Antibody, gp2B Antibody, Integrin alpha-IIb Antibody, ITGAB Antibody, GPIIb Antibody, HPA3 Antibody, Platelet-specific antigen BAK Antibody, CD41 Antibody, CD41 antigen Antibody, GPalpha IIb Antibody, GTA Antibody

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen.

Requested From: United States
Date Requested: 12/2/2016

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