Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Baboon, Monkey, Cynomolgus (tested or 100% immunogen sequence identity)
Protein G purified
IHC - Paraffin
IHC - Frozen (1:500 - 1:1000)
Flow Cytometry (1:50 - 1:100)
Specificity and Use
ITGA2 / CD49b antibody was raised against human CD49b.
Recognizes the human integrin alpha 2 subunit expressed by platelets, long term cultivated T cells, approximately 50% of monocytes and most adherent cell lines. Species cross-reactivity: cynomolgus monkey, rhesus monkey, baboon.
Suitable for use in Flow Cytometry and Immunohistochemistry (frozen). Flow Cytometry: 1:50-1:100; 10 ul labels 10^6 cells in 100ul. Immunohistochemistry (frozen): 1:500-1:1000.
PBS, 0.09% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.
ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.