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Anti-IRF5 Antibody (aa176-240) LS-C45031


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular IRF5 Antibodies

Anti-IRF5 Antibody (aa395-444) LS-C109630
Rabbit Polyclonal to Human IRF5
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig, Rabbit, Zebrafish
Western blot
Western blot Image
Anti-IRF5 Antibody (clone 2G9) LS-C133897
Mouse Monoclonal [clone 2G9] (IgG1,k) to Human IRF5
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human IRF5
Western blot, Immunoprecipitation, ELISA


Human IRF5
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified


  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation

Specificity and Use

IRF5 antibody was raised against recombinant human IRF5 (176-240aa) purified from E. coli.
Recognizes human interferon regulatory factor 5 (IRF5), a 58kD member of the IRF family which acts as a key regulator of interferon gene transcription, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells. The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented. Studies have shown that IRF5 can also regulate IFN gene transcription, but appears to be more restricted in its cellular expression and range of viral stimuli, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, including RANTES, MCP-1 and IP-10.
Western Blot: LS-C45031 detects a band of approximately 58kD in THP-1 cell lysates.


PBS, pH 7.4, 0.02% Thimerosal.
For research use only.

About IRF5

Q13568 NM_002200 NP_116032.1

IRF5 Antibody, Interferon regulatory factor 5 Antibody, IRF-5 Antibody, SLEB10 Antibody, IBD14 Antibody

IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats.

Requested From: United States
Date Requested: 10/25/2016

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