The Immunohistochemistry Antibody Company
|Human, Monkey, Rat, Bat, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)|
|Mouse, Bovine, Sheep, Zebrafish (at least 90% immunogen sequence identity)|
|IRF2 antibody was raised against synthetic peptide located between aa52-101 of human IRF2 (P14316, NP_002190). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Rat, Hamster, Elephant, Dog, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%); Mouse, Sheep, Bovine (92%); Pike, Zebrafish (90%); Turkey, Chicken, Xenopus (85%).|
|50 µl After adding water, will consist of PBS buffer with 2% sucrose|
|Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.|
|For research use only.|
IRF2 Antibody, IRF-2 Antibody, Interferon regulatory factor 2 AntibodySpecifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.