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Anti-IREB2 / IRP2 Antibody (aa489-503) IHC-plus™ LS-B4397

Note: This antibody replaces LS-C108131

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IREB2 / IRP2 Antibodies

Anti-IREB2 / IRP2 Antibody (aa1-100) IHC-plus™ LS-B675
Rabbit Polyclonal to Human IREB2 / IRP2
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IREB2 / IRP2 Antibody (aa434-483) LS-C80347
Rabbit Polyclonal (IgG) to Human IREB2 / IRP2
Human, Monkey, Dog, Horse, Pig
Western blot, ELISA
Unconjugated
Western blot Image
Anti-IREB2 / IRP2 Antibody (aa489-503) IHC-plus™ LS-B4397
Goat Polyclonal to Human IREB2 / IRP2
Human, Monkey, Pig
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human IREB2 / IRP2
Human, Monkey, Pig
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human IREB2 / IRP2
Goat
Human, Monkey, Pig (tested or 100% immunogen sequence identity)
Horse, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • ELISA (1:32000)

Specificity and Use

IREB2 / IRP2 antibody was raised against synthetic peptide C-SIHYEGSEYKLSHGS from an internal region of human IREB2 (NP_004127.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Pig (100%); Elephant, Horse, Rabbit (93%); Bovine (87%); Mouse, Rat, Dog, Opossum, Platypus (80%).
LS-E27113 - Lyophilized - 100 µg - $145.00
aa489-503
Human IREB2.
Western Blot: Approx 110kD band observed in Human Liver lysates (calculated MW of 105kD according to NP_004127.1). Recommended concentration: 1-3 ug/ml. An additional band of unknown identity was also consistently observed at 60kD. This band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About IREB2 / IRP2

P48200 NM_004136 P48200

IREB2 Antibody, ACO3 Antibody, Iron regulatory protein 2 Antibody, IRP2AD Antibody, IRE-BP 2 Antibody, IRP2 Antibody

RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Immunohistochemistry

Immunohistochemistry
Anti-IREB2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4397 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-IREB2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4397 concentration 3.75 ug/ml.

Western blot

Western blot
IREB2 antibody (0.3 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/7/2016

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