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Anti-IRAK4 / IRAK-4 Antibody (N-Terminus) LS-C8255

Catalog Size Price
LS-C8255-100 100 µg (0.25 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human IRAK4 / IRAK-4
Human, Rat
Immunofluorescence, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human IRAK4 / IRAK-4
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Immunoaffinity purified
Unmodified

Applications

  • Immunofluorescence (10 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

IRAK4 / IRAK-4 antibody was raised against synthetic peptide derived from the N-terminal region of the human IRAK4 (IL-1 receptor associated kinase 4) protein. The peptide sequence is identical in mouse, human and rat.
N-Terminus
Reacts with the human IRAK4 protein. On Western blots, it identifies a single band at ~52kD. Reactivity has been confirmed with human HeLa cell lysates. Reactivity with mouse and rat is expected based on sequence homology.
Suitable for use in Western Blot and Immunofluorescence. Western Blot: 1-3 ug/ml. Immunofluorescence: 10 ug/ml.

Packaging

PBS, pH 7.4, 0.1% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About IRAK4 / IRAK-4

Q9NWZ3 NM_016123 NP_057207.2

IRAK4 Antibody, IPD1 Antibody, IRAK-4 Antibody, NY-REN-64 Antibody, REN64 Antibody

Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.

Requested From: 
Date Requested: 5/20/2018

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