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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IRAK4 / IRAK‑4 Antibody (N‑Terminus) LS‑C8255
Antibody
IRAK-4 antibody LS-C8255 is an unconjugated rabbit polyclonal antibody to IRAK-4 (IRAK4) from human and rat. Validated for IF and WB.
Catalog
Size
Price
LS-C8255-100
100 µg (0.25 mg/ml)
Unavailable

Popular IRAK4 / IRAK-4 Products

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Antibody
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Product Description

IRAK-4 antibody LS-C8255 is an unconjugated rabbit polyclonal antibody to IRAK-4 (IRAK4) from human and rat. Validated for IF and WB.
About IRAK4 / IRAK-4
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. Q9NWZ3 NM_016123 NP_057207.2

IRAK4 Antibody, IPD1 Antibody, IRAK-4 Antibody, NY-REN-64 Antibody, REN64 Antibody


Specifications

Target
Human IRAK4 / IRAK-4
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Immunofluorescence (10 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
IRAK4 / IRAK-4 antibody was raised against synthetic peptide derived from the N-terminal region of the human IRAK4 (IL-1 receptor associated kinase 4) protein. The peptide sequence is identical in mouse, human and rat.
Epitope
N-Terminus
Specificity
Reacts with the human IRAK4 protein. On Western blots, it identifies a single band at ~52kD. Reactivity has been confirmed with human HeLa cell lysates. Reactivity with mouse and rat is expected based on sequence homology.
Usage
Suitable for use in Western Blot and Immunofluorescence. Western Blot: 1-3 ug/ml. Immunofluorescence: 10 ug/ml.
Presentation
PBS, pH 7.4, 0.1% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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