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Anti-IRAK4 / IRAK-4 Antibody (aa436-459) LS-C8256

Ordering

Wt. Vol. Conc. Price
100 µg - - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IRAK4 / IRAK-4 Antibodies

Anti-IRAK4 / IRAK-4 Antibody (aa38-54) IHC-plus™ LS-B2048
Rabbit Polyclonal (IgG) to Mouse IRAK4 / IRAK-4
Mouse, Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IRAK4 / IRAK-4 Antibody (aa2-13) IHC-plus™ LS-B4823
Goat Polyclonal to Human IRAK4 / IRAK-4
Human, Monkey, Bat, Horse
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IRAK4 / IRAK-4 Antibody (clone 2H9) IHC-plus™ LS-B10452
Mouse Monoclonal [clone 2H9] (IgG1) to Human IRAK4 / IRAK-4
Human, Monkey, Mouse
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human IRAK4 / IRAK-4
Human
Western blot
Unconjugated

Details

Human IRAK4 / IRAK-4
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey, Bovine, Horse, Rabbit (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

Western blot (0.5 µg/ml)

Specificity and Use

IRAK4 / IRAK-4 antibody was raised against kLH-conjugated, synthetic peptide corresponding to amino acids 436-459 (CLHEKKNKRPDIKKVQQLLQEMTA) of human IRAK4. The immunizing sequence has 21/24 identical amino acids in mouse. Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Porcine (100%); Gorilla, Monkey, Elephant, Horse (96%); Bovine, Rabbit, Platypus (92%); Mouse, Hamster, Bat (88%); Rat (83%).
aa436-459
Recognizes IRAK4, Mr ~52kD. Species cross-reactivity: Human. Predicted to cross-react with mouse based on sequence homology.
Suitable for use in Western Blot. Western Blot: 0.5 ug/ml detects IRAK4 in RIPA lysates from HeLa and A431 cells. HeLa cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-IRAK4 (0.5 ug/ml). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About IRAK4 / IRAK-4

Q9NWZ3 NM_016123 NP_057207.2

IRAK4 Antibody, IPD1 Antibody, IRAK-4 Antibody, NY-REN-64 Antibody, REN64 Antibody

Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.

Requested From: United States
Date Requested: 12/3/2016

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