Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human IRAK3 / IRAKM / IRAK-M
ICC, Western blot
Human IRAK3 / IRAKM / IRAK-M
Human, Mouse (tested or 100% immunogen sequence identity)
ICC (1:100 - 1:1000)
Western blot (1:500 - 1:3000)
Specificity and Use
IRAK3 / IRAKM / IRAK-M antibody was raised against recombinant fragment corresponding to a region within amino acids 58 and 357 of IRAK3 (SwissProt Q9Y616). Percent identity by BLAST analysis: Human (100%); Mouse (80%).
Human IRAK3 / IRAK M
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
IRAK3 Antibody, ASRT5 Antibody, IRAK M Antibody, IRAK-3 Antibody, IL1RAK M Antibody, IRAK-M Antibody, IRAKM Antibody
IRAK3 / IRAKM / IRAK-M is a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.