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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IRAK2 / IRAK‑2 Antibody (C‑Terminus) IHC‑plus™ LS‑B3201
Note: This antibody replaces LS-C487
IRAK-2 antibody LS-B3201 is an unconjugated rabbit polyclonal antibody to human IRAK-2 (IRAK2). Validated for ELISA, ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3201-50
50 µg (1 mg/ml)
Unavailable

Popular IRAK2 / IRAK-2 Products

Anti-IRAK2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2047 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3188 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, ELISA
Anti-IRAK2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6102 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
IRAK2 / IRAK-2 antibody. IHC(P): Rat Spleen Tissue.
Species: Human, Monkey, Mouse, Bat, Bovine, Guinea pig, Pig, Sheep
Applications: IHC, IHC - Paraffin, ICC, Western blot

Product Description

IRAK-2 antibody LS-B3201 is an unconjugated rabbit polyclonal antibody to human IRAK-2 (IRAK2). Validated for ELISA, ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About IRAK2 / IRAK-2
IRAK2, an IRAK type protein kinase, is a signal transducer for the immune response interleukin-1 receptor (IL-1R) signaling cascade. IRAK2 also has been associated with signaling cell death, potentially via the Fas-associated death domain protein/caspase-8 apoptotic pathway. Dominant negative forms of IRAK2 attenuate IL-1R-mediated NF-kappa B activation, suggesting that IRAK-2 may serve as a therapeutic target for inhibiting IL-1-induced inflammation. O43187 NM_001570 NP_001561.3

IRAK2 Antibody, Il1rak2 Antibody, IRAK-2 Antibody


Specifications

Target
Human IRAK2 / IRAK-2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Western blot (0.5 - 1 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E30169 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B3201. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
At least four isoforms of IRAK2 are known to exist; this antibody will detect all four isoforms. Anti-IRAK2 has no cross response to IRAK.
Usage
Immunohistochemistry: LS-B3201 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3201 was determined to be 5 ug/ml.
Presentation
PBS, 0.02% sodium azide.
Storage
Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.
Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.

Immunofluorescence

Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.
Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.

Western blot

Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.
Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.

Immunofluorescence

Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.
Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.

Western blot

Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.
Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.

Immunofluorescence

Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.
Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.

Western blot

Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunohistochemistry

Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.
Anti-IRAK2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3201 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.
Immunocytochemistry of mIRAK2 in A-20 cells with mIRAK2 antibody at 1 µg/ml.

Immunofluorescence

Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.
Immunofluorescence of IRAK2 in A20 cells with IRAK2 antibody at 10 ug/ml.

Western blot

Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Western blot of IRAK2 in RAW264.7 whole cell lysate with mIRAK2 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.


Requested From: 
Date Requested: 6/24/2018

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