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Anti-IRAK1 / IRAK Antibody (aa700-712) LS-C730

Note: This antibody replaces LS-C16070

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IRAK1 / IRAK Antibodies

Anti-IRAK1 / IRAK Antibody (clone 3F7) IHC-plus™ LS-B4360
Mouse Monoclonal [clone 3F7] (IgG2a,k) to Human IRAK1 / IRAK
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IRAK1 / IRAK Antibody (aa405-433) LS-C164426
Rabbit Polyclonal to Mouse IRAK1 / IRAK
Mouse
Western blot, Flow Cytometry
Unconjugated
Western blot Image
Anti-IRAK1 / IRAK Antibody (aa530-693, Biotin) LS-C225689
Mouse Monoclonal (IgG2a) to Human IRAK1 / IRAK
Human
Immunofluorescence, Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human IRAK1 / IRAK
Human, Monkey
Western blot, Immunoprecipitation
Unconjugated

Details

Human IRAK1 / IRAK
Rabbit
Human, Monkey (tested or 100% immunogen sequence identity)
Hamster, Rabbit (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • Western blot (0.5 - 1 µg/ml)
  • Immunoprecipitation

Specificity and Use

IRAK1 / IRAK antibody was raised against a peptide corresponding to amino acids 700-712 (DRQGPEESDEFQS) of human IRAK-1 (4). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Hamster, Panda, Rabbit (92%); Mouse, Bovine, Pig (85%).
aa700-712
An 80 kD band is observed. The is human, mouse, and rat (based on sequence) reactive, and has no cross reactivity to IRAK2.

Packaging

PBS, 0.02% sodium azide, 0.1 mg/ml BSA.
Long term: -70°C; Short term: +4°C
For research use only.

About IRAK1 / IRAK

P51617 NM_001569 NP_001560.2

IRAK1 Antibody, IRAK-1 Antibody, Pelle Antibody, Il1rak Antibody, IRAK Antibody, Pelle homolog Antibody

Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation.

Western blot

Western blot
Western blot of IRAK using antibody at 0.5 ug/ml against 15 ug/lane of HeLa (lane 1) and NIH 3T3 (lane 2) cell lysate.
 

Requested From: United States
Date Requested: 12/11/2016

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