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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IQGAP1 Antibody (C‑Terminus) LS‑C8231
IQGAP1 antibody LS-C8231 is an unconjugated mouse monoclonal antibody to IQGAP1 from human and monkey. Validated for ELISA, IP and WB.
Antibody
Catalog
Size
Price
LS-C8231-100
100 µg
$605

Popular IQGAP1 Products

Immunoperoxidase of monoclonal antibody to IQGAP1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 1 ug/ml]
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence
Detection of Human IQGAP1 by Immunohistochemistry and Immunofluorescence. Sample: FFPE sections of human breast carcinoma. Antibody: Affinity purified rabbit anti-IQGAP1 used at a dilution of 1:1000 (0.2 ug/ml) and 1:200 (1 ug/ml). Detection: DAB and Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain, cross-adsorbed Antibody DyLight 594 Conjugated used at a dilution of 1:100.
Species: Human, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Proximity Ligation Assay
Detection of Human IQGAP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-IQGAP1 used at a dilution of 1:100.
Species: Human, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence

Product Description

IQGAP1 antibody LS-C8231 is an unconjugated mouse monoclonal antibody to IQGAP1 from human and monkey. Validated for ELISA, IP and WB.
About IQGAP1
Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. P46940 NM_003870 NP_003861.1

IQGAP1 Antibody, HUMORFA01 Antibody, p195 Antibody, KIAA0051 Antibody, RasGAP-like with IQ motifs Antibody, SAR1 Antibody


Specifications

Target
Human IQGAP1
Host
Mouse
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1 - 2 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
IQGAP1 antibody was raised against a recombinant protein derived from the C-terminal fragment of human IQGAP1 protein.
Epitope
C-Terminus
Specificity
Recognizes the Cdc42-binding protein IQGAP1 and does not exhibit any cross-reactivity with the related IQGAP2 protein. Species cross-reactivity: IQGAP1 from human and monkey cells. It does not react with mouse, rat, or canine IQGAP1.
Usage
Suitable for use in ELISA, Western Blot and Immunoprecipitation. ELISA: 0.1-1 ug/ml. Western Blot: 1-2 ug/ml. Immunoprecipitation (native): 5 ug/IP reaction.
Presentation
PBS, pH 7.4, 0.1% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/21/2018

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