Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
IQGAP1 antibody was raised against a recombinant protein derived from the C-terminal fragment of human IQGAP1 protein.
Recognizes the Cdc42-binding protein IQGAP1 and does not exhibit any cross-reactivity with the related IQGAP2 protein. Species cross-reactivity: IQGAP1 from human and monkey cells. It does not react with mouse, rat, or canine IQGAP1.
Suitable for use in ELISA, Western Blot and Immunoprecipitation. ELISA: 0.1-1 ug/ml. Western Blot: 1-2 ug/ml. Immunoprecipitation (native): 5 ug/IP reaction.
PBS, pH 7.4, 0.1% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.