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IPO8 / Importin 8

importin 8

Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.

Gene Name: importin 8
Synonyms: IPO8, Imp8, Importin 8, Importin-8, Ran-binding protein 8, RAN binding protein 8, RANBP8
Target Sequences: NM_006390 NP_006381.2 O15397

☰ Filters
Antibodies (19)
Proteins (2)
Primary (19)
Recombinant (2)
IPO8 / Importin 8 (21)
Human (11)
Mouse (12)
Rat (2)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (5)
Orangutan (3)
IHC (2)
IHC-P (1)
WB (16)
ELISA (2)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (18)
goat (1)
IgG (6)
polyclonal pc (19)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (9)
aa417-622 (8)
aa646-695 (4)
aa1026-1037 (1)
aa850-900 (1)
aa987-1037 (1)
No (20)
Yes (1)
GST, N-terminus (1)
His-GST (1)
Human (1)
Mouse (1)
E. coli (1)
Wheat Germ Extract (1)
IPO8 / Importin 8 Antibody - ICC staining of HeLa cells using antibody (Importin-8) at 5 ug/ml.
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IPO8 / Importin 8 Rabbit anti-Human Polyclonal (aa850-900) Antibody
Human, Monkey
ICC, IF, WB
Unconjugated
100 µg/$386
IPO8 / Importin 8 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using IPO8 Polyclonal Antibody at dilution of 1:50.
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IPO8 / Importin 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IPO8 / Importin 8 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using IPO8 Polyclonal Antibody at dilution of 1:50.
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IPO8 / Importin 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
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IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
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IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$547; 1 ml/$649; 2 ml/$884; 5 ml/$1,475
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
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IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
Select
IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
Select
IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
Select
IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
Select
IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
IPO8 / Importin 8 Antibody - Western blot of recombinant IPO8 / Importin 8.
Select
IPO8 / Importin 8 Rabbit anti-Mouse Polyclonal (aa417-622) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
IPO8 / Importin 8 Antibody - Goat Anti-RANBP8 / IPO8 Antibody (4µg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Similar results were obtained after antigen retrieval at pH9.
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IPO8 / Importin 8 Goat anti-Human Polyclonal (aa1026-1037) Antibody
Human, Monkey
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
Select
IPO8 / Importin 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
IPO8 / Importin 8 Antibody - IPO8 / Importin 8 antibody Western Blot of Fetal Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IPO8 / Importin 8 Rabbit anti-Human Polyclonal (aa646-695) Antibody
Human
WB
Unconjugated
100 µl/$424
IPO8 / Importin 8 Antibody - IPO8 / Importin 8 antibody Western Blot of Fetal Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IPO8 / Importin 8 Rabbit anti-Human Polyclonal (aa646-695) (HRP) Antibody
Dog, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
IPO8 / Importin 8 Antibody - IPO8 / Importin 8 antibody Western Blot of Fetal Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IPO8 / Importin 8 Rabbit anti-Human Polyclonal (aa646-695) (Biotin) Antibody
Dog, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
IPO8 / Importin 8 Antibody - IPO8 / Importin 8 antibody Western Blot of Fetal Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IPO8 / Importin 8 Rabbit anti-Human Polyclonal (aa646-695) (FITC) Antibody
Dog, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
IPO8 / Importin 8 Antibody - Detection of Human RanBP8 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody: Affinity purified rabbit anti-RanBP8 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Select
IPO8 / Importin 8 Rabbit anti-Human Polyclonal (aa987-1037) Antibody
Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
IPO8 / Importin 8 Antibody - Western blot analysis of extracts of various cell lines, using IPO8 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Select
IPO8 / Importin 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IPO8 / Importin 8 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
IPO8 / Importin 8 Protein - Recombinant Importin 8 By SDS-PAGE
Select
E. coli
His-GST
55.9 kDa
50 µg/$472; 10 µg/$286; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Viewing 1-21 of 21 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).