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IPO5 / RANBP5

importin 5

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.

Gene Name: importin 5
Synonyms: IPO5, IMB3, Importin 5, Importin subunit beta-3, Imp5, Importin-5, Importin beta-3 subunit, Karyopherin beta-3, KPNB3, Karyopherin (importin) beta 3, Pse1, RAN binding protein 5, Ran-binding protein 5, Ran_GTP binding protein 5, RANBP5
Target Sequences: NM_002271 NP_002262.3 O00410

☰ Filters
Antibodies (13)
Proteins (3)
Over-Expression Lysate (2)
Primary (13)
Recombinant (1)
IPO5 / RANBP5 (16)
Human (13)
Mouse (7)
Rat (3)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
IHC (2)
IHC-P (2)
WB (13)
ELISA (2)
IF (3)
Peptide-ELISA (1)
rabbit (8)
mouse (5)
Product Group
IHCPlus (2)
IgG (3)
IgG1 (2)
IgG1,k (1)
IgG2b (1)
monoclonal mc (4)
polyclonal pc (9)
1C4 (1)
OTI1C5 (1)
OTI3B8 (1)
OTI4C3 (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (10)
aa143-192 (4)
aa1-220 (3)
No (16)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
IPO5 / RANBP5 Antibody - Immunohistochemistry of paraffin-embedded mouse lung tissue.
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IPO5 / RANBP5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IPO5 / RANBP5 Antibody - Anti-IPO5 / Importin 5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IPO5 / RANBP5 Mouse anti-Human Monoclonal (1C4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
IPO5 / RANBP5 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IPO5 / RANBP5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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IPO5 / RANBP5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
IPO5 / RANBP5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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IPO5 / RANBP5 Mouse anti-Human Polyclonal Antibody
Rat, Human
IF, WB
Unconjugated
50 µg/$705
IPO5 / RANBP5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IPO5. (Right lane) cDNA for 48 hrs and lysed
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IPO5 / RANBP5 Mouse anti-Human Monoclonal (aa1-220) (OTI1C5) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$434
IPO5 / RANBP5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IPO5. (Right lane) cDNA for 48 hrs and lysed
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IPO5 / RANBP5 Mouse anti-Human Monoclonal (aa1-220) (OTI4C3) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$434
IPO5 / RANBP5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IPO5. (Right lane) cDNA for 48 hrs and lysed
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IPO5 / RANBP5 Mouse anti-Human Monoclonal (aa1-220) (OTI3B8) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$434
IPO5 / RANBP5 Antibody - IPO5 / Importin 5 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IPO5 / RANBP5 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
IPO5 / RANBP5 Antibody - IPO5 / Importin 5 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IPO5 / RANBP5 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
IPO5 / RANBP5 Antibody - IPO5 / Importin 5 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IPO5 / RANBP5 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
IPO5 / RANBP5 Antibody - IPO5 / Importin 5 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IPO5 / RANBP5 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
IPO5 / RANBP5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
IPO5 / RANBP5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
125.4 kDa
20 µg/$150
IPO5 / RANBP5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
125.4 kDa
100 µg/$494
Viewing 1-16 of 16 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).