Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [P1F6]
Protein A purified
Specificity and Use
Human UCLA P3 cells (lung carcinoma).
Recognizes human integrin aVb5. Species cross-reactivity: Chicken.
Suitable for use in the inhibition of attachment of HT29 cells to vitronectin, Inhibition of attachment of carcinoma and melanoma cells to vitronectin, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation, Flow Cytometry and ELISA. Inhibition of attachment of HT29 cells to vitronectin: >1:1000. Immunocytochemistry (acetone fixed only): 1:1500. For use on human carcinomas, normal epithelium and keratinocytes. Immunohistochemistry: Acetone or paraformaldehyde fixed tissues. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.