Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone DATK32] (IgG2a) to Mouse Integrin Alpha4 Beta7 / LPAM-1
PE, Cy5 Conjugated
Rat Monoclonal [clone DATK32 (DATK-32)] (IgG2a,k) to Mouse Integrin Alpha4 Beta7 / LPAM-1
Mouse Integrin Alpha4 Beta7 / LPAM-1
Mouse (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [DATK32 (DATK-32)]
Specificity and Use
Mouse Integrin Alpha4 Beta7 (ITGA4/ITGB7)
This DATK32 (DATK-32) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Store at 4°C. Do not freeze.
For research use only.
About Integrin Alpha4 Beta7 / LPAM-1
LPAM-1 (integrin alpha 4 beta 7) mediates lymphocyte attachment within the extracellular matrix (ECM) by adhering to the connecting segment (CS)-1 site of fibronectin (FN). It is upregulated in atherosclerotic lesions and is involved in atherosclerosis progression.
Staining of C57Bl/6 splenocytes with FITC anti-mo/hu B220 (RA3-6B2) (LS-C105879) and 0.25 ug of Biotin anti-mouse LPAM-1 (DATK32)followed by Streptavidin-PE. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of C57Bl/6 splenocytes with FITC anti-mo/hu B220 (RA3-6B2) (LS-C105879) and 0.25 ug of Biotin Rat IgG2a isotype control followed by Streptavidin-PE. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.