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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Integrin Alpha V Beta 3 Antibody (clone LM609) LS‑C15964
Integrin Alpha V Beta 3 antibody LS-C15964 is an unconjugated mouse monoclonal antibody to Integrin Alpha V Beta 3 from human, avian, bovine and other species. Validated for Flow, ICC, IF, IHC and IP.
Antibody
Catalog
Size
Price
LS-C15964-100
100 µg (1 mg/ml)
Unavailable

Popular Integrin Alpha V Beta 3 Products

Antibody
Species: Human
Applications: Immunoprecipitation, Flow Cytometry, Functional Assay
Antibody
Species: Human, Monkey, Bovine, Dog, Pig, Rabbit, Chicken, Avian
Applications: IHC, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Functional Assay
Antibody
Species: Human, Monkey, Bovine, Dog, Pig, Rabbit, Chicken
Applications: Immunofluorescence, Immunoprecipitation, Functional Assay
Antibody
Species: Human
Applications: Immunoprecipitation, Flow Cytometry, ELISA

Product Description

Integrin Alpha V Beta 3 antibody LS-C15964 is an unconjugated mouse monoclonal antibody to Integrin Alpha V Beta 3 from human, avian, bovine and other species. Validated for Flow, ICC, IF, IHC and IP.

Specifications

Target
Human Integrin Alpha V Beta 3
Host
Mouse
Reactivity
Human, Monkey, Bovine, Dog, Pig, Rabbit, Chicken, Avian (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [LM609]
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • ICC
  • Immunofluorescence (5 - 10 µg/ml)
  • Immunoprecipitation
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Immunogen
Purified adhesion receptor from the human melanoma cell line M21.
Specificity
Recognizes the human vitronectin receptor aVb3 complex, an RGD-directed adhesion receptor. Species cross-reactivity: bovine, chicken, monkey, porcine, canine, rabbit and avian. Not reactive with rat tissue.
Usage
Suitable for use in Immunoprecipitation, Immunofluorescence, Flow Cytometry, Immunohistochemistry (frozen sections only), Immunocytochemistry and Blocking. Immunoprecipitation: Precipitates integrin alpha V beta3 complex. When resolved by SDS-PAGE under reducing conditions, bands are observed at ~130kD corresponding to the alpha V subunit and at ~105kD corresponding to the beta3 subunit. Flow Cytometry: 1-3 ug/0.5x1E6cells in 100 ul volume. Immunofluorescence: 5-10 ug/ml for staining of bFGF-treated 6mm cryosections of chick chorioallantoic membrane fixed with acetone. Also effective on 4% paraformaldehyde fixed, frozen tissues and cells. Not effective for immunohistochemical staining of paraffin-embedded tissue sections. Blocking: Inhibits adhesion of cells to vitronectin coated surfaces at 10-25 ug/ml. Positive control: Human myeloma cell lines M21 and MoalphaV.
Presentation
PBS, pH 7.1. No preservatives added.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/17/2018

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