Integrin Alpha V Beta 3

Mouse

Human (tested or 100% immunogen sequence identity)

Monoclonal

A10-33/1

Unconjugated

Affinity purified

Unmodified

Human melanoma cell lines.

The antigen is GPIIb-IIIa located on the cell surface, the epitope has not been further characterized. Antigen distribution: Isolated cells: The antigen is found on the surface of isolated human, bovine and murine endothelial cells from various organs. It is also found on various tumorous cells such as melanoma, teratoma, neuroblastoma and carcinoma cells. The antigen is absent on glioblastoma and on T and B lymphoblastoid cells Tissue sections: The antigen is located on endothelial cells of large vessels of the liver where it is more pronounced in veins than in arteries. In contrast to the liver, the antigen is found on endothelial cells of capillaries in the lung, gall bladder and skin. The antigen can also be found on melanoma, especially in metastasizing melanomas, and in carcinomas. Reactions of A 10-33/1 with nervous tissue have been reported. Specificity: Human: Endothelial cells of various organs. Other: Bovine and murine endothelial cells.

• IHC
• IHC - Frozen (1:200 - 1:400)

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal

Reconstitute with 0.5ml distilled H2O.

Store at 4°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.