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Anti-Insulin C-Peptide Antibody (N-Terminus, clone CII-11) LS-C58406


Wt. Vol. Conc. Price
200 µg - - $330
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

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Mouse Monoclonal [clone CII-11] (IgG1) to Rat Insulin C-Peptide
Rat, Mouse


Rat Insulin C-Peptide
Rat, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CII-11]
Affinity purified



Specificity and Use

Fragments of rat C-peptide conjugated to a carrier protein.
Recognizes rat C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes an epitope in the N-terminal region of rat and mouse C-peptide I and II with almost equal affinity. Reacts very weakly with rat proinsulin. May be used to detect rat or mouse C-peptide I or II in ELISA assays.
ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA to detect rat C-peptide I or II together with LS-C58409 as capture reagent. This sandwich ELISA configuration is only suitable for the detection of rat and not mouse C-peptide I or II.


PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About Insulin C-Peptide

Requested From: United States
Date Requested: 10/26/2016

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