Human Insulin C-Peptide

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

7E10

Unconjugated

Protein A purified

Unmodified

Recombinant C-peptide.

Recognizes human C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+</sup concentration and subsequent stimulation of N+, K+ -ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Levels of C-peptide can be used to distinguish between type 1 and type 2 diabetes. Patients with type 1 diabetes will usually have decreased levels of C-peptide, while patients with type 2 diabetes will have normal or higher than normal levels. Does not cross-react with human, bovine, porcine, mouse or rat insulin.

• ELISA

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

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