Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Pig, Human, Rat (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:50)
IHC - Frozen (1:50)
Specificity and Use
Insulin antibody was raised against porcine insulin.
Recognizes porcine insulin. Species cross-reactivity: Human, rat.
Suitable for use in Immunohistochemistry and ELISA: 1:50. Immunohistochemistry (Frozen and paraffin without proteolytic treatment): 1:50 using the Indirect method. Dilute immediately before use with PBS or TRIS.
0.02% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified.