INSIG1

insulin induced gene 1

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.

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Products

Antibodies (35)

Proteins (4)

Type

Over-Expression Lysate (4)

Primary (35)

Target

INSIG1 (39)

Reactivity

Human (35)

Mouse (7)

Rat (7)

Bat (3)

Bovine (6)

Chicken (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Goat (6)

Guinea pig (3)

Hamster (6)

Horse (6)

Monkey (6)

Orangutan (6)

Pig (6)

Rabbit (6)

Sheep (3)

Xenopus (6)

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Application

IHC (13)

IHC-P (11)

WB (32)

Flo (1)

ELISA (8)

IF (3)

IP (1)

Peptide-ELISA (1)

Host

rabbit (35)

Product Group

IHCPlus (2)

Isotype

IgG (20)

Clonality

polyclonal pc (35)

Format

APC Conjugated (1)

Biotin Conjugated (7)

DY488 Conjugated (1)

DY550 Conjugated (1)

DY650 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (1)

Unconjugated (11)

Epitope

C-Terminus (8)

aa36-63 (7)

Internal (5)

aa63-112 (4)

aa71-120 (4)

aa1-100 (1)

Publications

No (39)

Tag

Myc-DDK (Flag) (4)

Species

Human (2)

Source

293T Cells (2)

HEK 293 Cells (2)

Select

INSIG1 Antibody (aa63-112) LS-B6815

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa63-112) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

INSIG1 Antibody (aa63-112, HRP) LS-C439780

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa63-112) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Bat, Rat, Hamster, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

INSIG1 Antibody (aa63-112, Biotin) LS-C439777

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa63-112) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Bat, Rat, Hamster, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

INSIG1 Antibody (aa63-112, FITC) LS-C439778

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa63-112) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Bat, Rat, Hamster, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

INSIG1 Antibody LS-C672360

Antibody:

INSIG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

INSIG1 Antibody LS-C666459

Antibody:

INSIG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

IHC-plus™ INSIG1 Antibody (aa1-100) LS-B2420

(4.0) Rating

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa1-100) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

INSIG1 Antibody (Internal, Biotin) LS-C141458

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

Select

INSIG1 Antibody (Internal, DY650) LS-C141459

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (Internal) (DY650) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

Select

INSIG1 Antibody (Internal, DY488) LS-C141460

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (Internal) (DY488) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

Select

INSIG1 Antibody (Internal, DY550) LS-C141462

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (Internal) (DY550) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY650
• DY488
• DY550

• Unconjugated
• Biotin
• DY650
• More...
  • DY488
  • DY550

Select

INSIG1 Antibody (aa36-63) LS-C165254

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

INSIG1 Antibody LS-C802904

Antibody:

INSIG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

INSIG1 Antibody (aa36-63) LS-C327623

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

INSIG1 Antibody (aa36-63, HRP) LS-C547110

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

200 µl/$952

Select

INSIG1 Antibody (aa36-63, Biotin) LS-C527000

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

INSIG1 Antibody (aa36-63, FITC) LS-C278345

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

INSIG1 Antibody (aa36-63, PE) LS-C278346

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

INSIG1 Antibody (aa36-63, APC) LS-C278344

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa36-63) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

INSIG1 Antibody (Internal) LS-C70714

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$649

Select

INSIG1 Antibody (C-Terminus) LS-C110485

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

INSIG1 Antibody (C-Terminus, HRP) LS-C439782

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

INSIG1 Antibody (C-Terminus, Biotin) LS-C439779

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

INSIG1 Antibody (C-Terminus) LS-C101823

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

INSIG1 Antibody (aa71-120) LS-C101825

Antibody:

INSIG1 Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Viewing 1-25 of 39 product results

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