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Anti-INSIG1 Antibody (Internal) LS-C70714

Catalog Size Price
LS-C70714-100 100 µl Unavailable

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34 INSIG1 Antibodies

Most Popular INSIG1 Antibodies

Anti-INSIG1 Antibody (aa63-112) IHC-plus™ LS-B6815
Rabbit Polyclonal to Human INSIG1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-INSIG1 Antibody LS-C672360
Rabbit Polyclonal (IgG) to Human INSIG1
Immunohistochemistry - Paraffin Image
Anti-INSIG1 Antibody (Biotin) LS-C672361
Rabbit Polyclonal (IgG) to Human INSIG1
Biotin Conjugated
Anti-INSIG1 Antibody (FITC) LS-C672363
Rabbit Polyclonal (IgG) to Human INSIG1
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Anti-INSIG1 Antibody (HRP) LS-C672364
Rabbit Polyclonal (IgG) to Human INSIG1
HRP Conjugated

100% Guaranteed
Rabbit Polyclonal to Human INSIG1
Western blot


Human INSIG1
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


Western blot

Specificity and Use

INSIG1 antibody was raised against a synthetic peptide representing an internal region of the human protein (between residues 1-100) according to Swiss-Prot# O15503. Homology: 100% with human protein. No other significant species homology.
This antibody is specific for Insig1 but not Insig2. Species cross-reactivity: This antibody reacts with human protein. Other species have not been tested.
Suitable for use in Western Blot. Positive control: HepG2 lysate.


PBS + 30% glycerol.
For research use only.

About INSIG1

O15503 NM_005542 NP_005533.2

INSIG1 Antibody, Cl-6 Antibody, CL6 Antibody, INSIG-1 Antibody, Insulin induced gene 1 Antibody, Insulin-induced gene 1 protein Antibody, INSIG-1 membrane protein Antibody

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78.

Requested From: 
Date Requested: 3/17/2018

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