Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 15A6] (IgG2a) to Influenza Virus Influenza A Virus H5
Influenza Virus Influenza A Virus H5
Influenza Virus (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [15A6]
Specificity and Use
Purified Avian Influenza Virus Type A (H5N1).
Detects hemagglutinin H5 from the Influenza A virus H5N1. Influenza A belongs to the Orthomyxoviridae family, and is a negative sense single-stranded RNA virus which results in respiratory disease. Hemagglutinin is an antigenic glycoprotein which allows viral attachment and entry into the cell. Sixteen subtypes of hemagglutinin (H1-H16) have been described, of which H1, H2 and H3 infect humans. H5 and H7 normally result in avian disease, with some highly pathogenic H5N1 strains causing 100% mortality in poultry. H5N1 has in some cases mutated to infect humans, with 60% mortality. Hemagglutinin is one of the most medically relevant antigens on influenza as it is a target for antiviral drugs and antibodies. May be used to detect Influenza H5N1 in ELISA assays.
ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with LS-C58231 as a capture reagent.